“Type 1 diabetes in pregnancy is associated with distinct changes in the composition and function of the gut microbiome.”

The latest ENDIA Study paper published this year reveals how women diagnosed with type 1 diabetes (T1D) tend to have a more pro-inflammatory gut microbiome during pregnancy. This is associated with evidence of intestinal inflammation.

It is possible that these changes contribute to an increased risk of pregnancy complications. These complications could potentially be modified by diet.

Interestingly, of children born with a mother, father or sibling diagnosed with T1D (as is the case for our ENDIA children), children whose mother has T1D have the lowest risk of developing T1D themselves. So there is possibly also some protective effect.

You can read the paper here: https://doi.org/10.1186/s40168-021-01104-y

Or watch the video summary prepared with thanks to Research Square: